November 17, 2025
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9 min read

What Causes Lymph Nodes To Swell Under The Arm?

Written by:

Deborah Kellogg

November 17, 2025

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If you’ve noticed some swollen lymph nodes under your arm, don’t worry too much. This condition—called axillary lymphadenopathy—often means that your immune system is hard at work keeping you healthy. These little bean-shaped glands act like filters, and when they catch anything from germs to abnormal cells, they can swell up.

1. Infections (Most Common Cause)

When your body senses an infection in areas like your arm, chest, or breast, your armpit lymph nodes jump into action. They work hard to filter out any germs and help fight off the infection, which is why they might swell up. Here are some examples of situations that can cause this:

  • Viral Infections: Just like with the common cold or the flu, there are other illnesses out there that can affect us, such as mononucleosis (often called mono), measles, or even HIV.
  • Bacterial Infections: You might encounter a few different skin infections, like cellulitis in your arm or hand. There are also strep infections to be aware of, and even Cat Scratch Disease, which can happen if you’ve been scratched or bitten by a cat.
  • Vaccinations: After getting recent vaccinations, such as the COVID-19 or flu shot, you might notice some temporary swelling in the lymph nodes near your armpit.

2. Inflammatory and Autoimmune Disorders

Certain conditions that lead to inflammation throughout the body can also cause your lymph nodes to swell:

  • Rheumatoid Arthritis
  • Lupus
  • Sarcoidosis

3. Cancer (Less Common)

Swollen lymph nodes might not happen all the time, but sometimes they can be a sign of something more serious, like cancer. This could either come from the lymph system itself or might have spread from another area in the body:

  • Lymphoma is a type of cancer that affects the lymphatic system, while leukemia impacts the blood-forming tissues in our bodies.
  • Metastatic cancer, especially when it comes to breast cancer, can spread to the lymph nodes, particularly those in the armpit. This happens because most of the lymph fluid from the breast drains into the armpit nodes.

Other Causes

  • Injury or Trauma to the arm or nearby area.
  • Allergies or reactions to certain medications.

Swollen lymph nodes usually appear as a normal response to infections, so they’re often nothing to worry about. But if you notice that your lymph nodes are swollen for no clear reason, sticking around for more than two to four weeks, getting bigger, feeling hard and immobile, or if you're experiencing other symptoms like unexpected weight loss, fever, or night sweats, it’s a good idea to check in with your doctor for a proper diagnosis.

What symptoms are related to a lump under the armpit?

Getting to know what's behind a lump under your arm is just the beginning; paying attention to any other related symptoms is very important, too. That lump, which doctors call an axillary mass, is often just a swollen lymph node. However, the signs that come along with it can help figure out what's causing it—be it a minor local infection or something more complicated.

If you've noticed an armpit lump, it can be concerning. Here are some common symptoms that might go along with it:

  • Changes in the lump itself: That lump you’re noticing could feel pain or tender when you touch it, but it might not hurt at all. Depending on what’s going on, it can be soft, firm, or even hard. It might move around, while other times it feels fixed in place. Sometimes, the skin over the lump might look red or feel warm.
  • Signs of Infection: Swollen lymph nodes are often caused by an infection, and when that happens, you might notice some common signs of illness. These can include things like a fever, a sore throat, a cough, or a runny nose. You might also feel unwell (malaise) or fatigue.
  • Systemic or Widespread Symptoms: If you're dealing with some health issues, especially the more serious ones, you might notice that a lump comes with some other signs that can affect your entire body. These could include things like:
    • Unexplained weight loss
    • Night sweats
    • Swelling of other lymph nodes in the neck or groin area
    • Persistent tiredness or fatigue
  • Skin-Related Symptoms: If you’ve noticed a lump that seems to be a skin issue—like a boil, cyst, or rash—there are a few signs to look out for. You might see some redness around the area, maybe some pus or discharge, and possibly experience itching or other types of skin irritation.
  • Breast-Related Symptoms (especially in women): If you notice an armpit lump, it might be linked to some changes happening in your breast, like a lump in the breast tissue or even some tenderness.

If you notice any unexplained or persistent lumps, it's a good idea to chat with a healthcare provider. They can help figure out what's going on and make sure everything is okay.

Treatments For Lymph Node Swelling In The Armpit

Once you have a good grasp of what the lump under your armpit might be like and what symptoms you're experiencing, the next important step is figuring out the right treatment for it. If you've noticed a swollen lymph node, it’s important to remember that it’s usually a sign of something else going on in your body, not the main issue itself. The best approach is to get to the root of the problem. This could be anything from a harmless local infection to a more serious condition that might need specialized care.

General Self-Care and Symptom Relief

If you're dealing with some common swelling from a minor infection, here are a few simple home care tips that can help you feel more comfortable:

  • Warm Compresses: Using a warm, damp washcloth or a heating pad on your armpit can be really soothing. It helps ease any pain and gets the blood flowing, which might just help speed up healing.
  • Over-the-Counter Pain Relievers: If you're dealing with pain or feeling under the weather, over-the-counter meds like ibuprofen (you might know it as Advil or Motrin) or acetaminophen (that's Tylenol) can really help. Just be sure to follow the instructions on the package for safe use.
  • Rest and Hydration: Getting enough rest and staying well-hydrated are very important for your immune system. They help your body do its best work when fighting off any infections.

Medical Treatment for Specific Causes

If the lump doesn’t go away, seems to get bigger, or if you're experiencing any other serious symptoms, it's a good idea to see a doctor. They can help figure out what’s going on and guide you toward the right treatment:

  • Bacterial Infection: If the swelling is due to a bacterial infection—like a skin infection or some other health issue—your healthcare provider will likely recommend a course of antibiotics to help you feel better.
  • Viral Infection: If you're dealing with swelling from common viruses like the cold, flu, or mononucleosis, antibiotics won't help in this case. The best approach is to take care of yourself and use some supportive measures until your body fights off the virus. For more serious conditions like HIV, though, antiviral medications can really help manage the primary condition.
  • Abscess or Cyst: If you have a lymph node or a skin issue, like a boil or cyst, that has developed an abscess (which is just a fancy way of saying there's a collection of pus), you might need to have a minor surgical procedure to drain the fluid.
  • Autoimmune Disorders: If you're dealing with swelling from an autoimmune disease like Lupus or Rheumatoid Arthritis, the treatment usually focuses on addressing the root of the issue, often involving specific immune-suppressing or anti-inflammatory medications.
  • Cancer (Malignancy): If it turns out that the swelling in your lymph nodes is due to cancer, like breast cancer or lymphoma, don’t worry—your doctor will refer you to an oncologist who specializes in treating cancer. They’ll guide you through the treatment options, which can include a mix of surgery (like removing lymph nodes), chemotherapy, radiation therapy, or targeted therapy.

It's really important to reach out to a healthcare professional if you're experiencing swelling that you can't explain, especially if it sticks around for more than a couple of weeks or comes with other symptoms like weight loss, fever, or night sweats.

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